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Cycle Analytics
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Maureen MUSCAT
FilterDCA
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994652a1
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994652a1
authored
Dec 18, 2019
by
Maureen MUSCAT
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994652a1
### FilterDCA
### FilterDCA
### interpretable supervised contact prediction using inter-domain coevolution
### interpretable supervised contact prediction using inter-domain coevolution
FilterDCA used 2 features to compute a probability of being a contact for a cople (i,j) in domain1 and domain2.
FilterDCA used 2 features to compute a probability of being a contact for a co
u
ple (i,j) in domain1 and domain2.
The first fea
uture is the result of the method plmDCA
The first fea
ture is the result of the method plmDCA.
The second one is a pattern score w
ich can be computed using the script and the maps give
n.
The second one is a pattern score w
hich is computed by apply severals maps on the dca score matrix and keeping the best correlatio
n.
To use the script you need:
To use the script you need:
-
the result of plmDCA for the join-MSA of the 2 domains ;
-
the result of plmDCA for the join-MSA of the 2 domains ;
...
@@ -13,7 +13,7 @@ To use the script you need:
...
@@ -13,7 +13,7 @@ To use the script you need:
In the 2 folders you can find:
In the 2 folders you can find:
-
the 6 maps (3 corresponding to helix-helix contact, and 3 for strand-strand contacts) for each of the possibles size (5, 13, 21, 37, 45 or 69)
-
the 6 maps (3 corresponding to helix-helix contact, and 3 for strand-strand contacts) for each of the possibles size (5, 13, 21, 37, 45 or 69)
-
the classifier
, and the 'min' 'max' and value
to normalise the correlation/ pattern score
-
the classifier
and the 'min'/'max' values
to normalise the correlation/ pattern score
You can then produice :
You can then produice :
-
the pattern score: the best correlation score matrix
-
the pattern score: the best correlation score matrix
...
...
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