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Cycle Analytics
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Maureen MUSCAT
FilterDCA
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994652a1
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994652a1
authored
Dec 18, 2019
by
Maureen MUSCAT
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994652a1
### FilterDCA
### interpretable supervised contact prediction using inter-domain coevolution
FilterDCA used 2 features to compute a probability of being a contact for a cople (i,j) in domain1 and domain2.
The first fea
uture is the result of the method plmDCA
The second one is a pattern score w
ich can be computed using the script and the maps give
n.
FilterDCA used 2 features to compute a probability of being a contact for a co
u
ple (i,j) in domain1 and domain2.
The first fea
ture is the result of the method plmDCA.
The second one is a pattern score w
hich is computed by apply severals maps on the dca score matrix and keeping the best correlatio
n.
To use the script you need:
-
the result of plmDCA for the join-MSA of the 2 domains ;
...
...
@@ -13,7 +13,7 @@ To use the script you need:
In the 2 folders you can find:
-
the 6 maps (3 corresponding to helix-helix contact, and 3 for strand-strand contacts) for each of the possibles size (5, 13, 21, 37, 45 or 69)
-
the classifier
, and the 'min' 'max' and value
to normalise the correlation/ pattern score
-
the classifier
and the 'min'/'max' values
to normalise the correlation/ pattern score
You can then produice :
-
the pattern score: the best correlation score matrix
...
...
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