Commit 994652a1 by Maureen MUSCAT

Initial commit

parent 66d2e09b
### FilterDCA ### FilterDCA
### interpretable supervised contact prediction using inter-domain coevolution ### interpretable supervised contact prediction using inter-domain coevolution
FilterDCA used 2 features to compute a probability of being a contact for a cople (i,j) in domain1 and domain2. FilterDCA used 2 features to compute a probability of being a contact for a couple (i,j) in domain1 and domain2.
The first feauture is the result of the method plmDCA The first feature is the result of the method plmDCA.
The second one is a pattern score wich can be computed using the script and the maps given. The second one is a pattern score which is computed by apply severals maps on the dca score matrix and keeping the best correlation.
To use the script you need: To use the script you need:
- the result of plmDCA for the join-MSA of the 2 domains ; - the result of plmDCA for the join-MSA of the 2 domains ;
...@@ -13,7 +13,7 @@ To use the script you need: ...@@ -13,7 +13,7 @@ To use the script you need:
In the 2 folders you can find: In the 2 folders you can find:
- the 6 maps (3 corresponding to helix-helix contact, and 3 for strand-strand contacts) for each of the possibles size (5, 13, 21, 37, 45 or 69) - the 6 maps (3 corresponding to helix-helix contact, and 3 for strand-strand contacts) for each of the possibles size (5, 13, 21, 37, 45 or 69)
- the classifier, and the 'min' 'max' and value to normalise the correlation/ pattern score - the classifier and the 'min'/'max' values to normalise the correlation/ pattern score
You can then produice : You can then produice :
- the pattern score: the best correlation score matrix - the pattern score: the best correlation score matrix
......
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