Modified README.

README.md

@@ -4,15 +4,18 @@
 # PRESCOTT: Population awaRe Epistatic and StruCtural mOdel of muTational effecTs                                                                                                             
 
 ## Introduction
-PRESCOTT is a program predicting mutational effects of a protein based on population, evolutionary and structural information.
-It can calculate effects of single point mutations and multiple point mutations.  
+PRESCOTT is a package predicting mutational effects in a protein based on population, evolutionary and structural information.
+It is made up of two main programs: escott and prescott.
+
+ESCOTT can calculate effects of single point mutations and multiple point mutations. On the other hand, PRESCOTT incorporates
+population frequencies into ESCOTT predictions. Therefore, you need to run ESCOTT first to have predictions of mutational effects. 
 We recommend using PRESCOTT via our web site or our docker image. 
 
 
 
 ## Input Data Requirements
 
-PRESCOTT requires two files:
+ESCOTT requires two files:
 * a multiple sequence alignment (MSA) file in fasta format (mandatory):
 
     Your query protein must be the first sequence in the fasta file. In addition, the query sequence should not contain any gaps. 
@@ -40,7 +43,7 @@ A quick help can be accessed by typing
 escott --help
 ```
 
-By default, GEMME will predict the effect of all possible single mutations at all positions in the 
+By default, ESCOTT will predict the effect of all possible single mutations at all positions in the 
 query sequence. Alternatively, a set of single or multiple mutations can be given with the option -m.
 Eachline of the file should contain a mutation (e.g. D136R) or combination of mutations separated 
 by commas (or colons) and ordered according to their positions in the sequence (e.g. D136R,V271A).