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a9c26ea9 · righetti2 · d878b113 · a9c26ea9
Commit a9c26ea9 authored Sep 25, 2024 by righetti2
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GO_Terms_with_Trends.tsv Datasets/GO_Terms_with_Trends.tsv +398 -0

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--- a/Datasets/GO_Terms_with_Trends.tsv
+++ b/Datasets/GO_Terms_with_Trends.tsv
+Genes (ENS ID ~ Gene Name)	Count	Neanderthal	Ancient sapiens
+Digestion			
+GO:0007586~digestion	5		
+ENSG00000204140 ~ CLPSL1		+	+
+ENSG00000137392 ~ CLPS		+	+
+Carbohydrates			
+GO:0044723~single-organism carbohydrate metabolic process	9		
+ENSG00000237763/ENSG00000174876/ENSG00000187733 ~ AMY1A/B/C		-	
+ENSG00000135226 ~ UGT2B28		-	
+ENSG00000173531 ~ MST1		+	+
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000127415 ~ IDUA		+	+
+ENSG00000137331 ~ IER3 (IEX-1)			+
+GO:0005975~carbohydrate metabolic process	9		
+ENSG00000237763/ENSG00000174876/ENSG00000187733 ~ AMY1A/B/C		-	
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000127415 ~ IDUA		+	+
+ENSG00000135226 ~ UGT2B28		-	
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000173531 ~ MST1		+	+
+GO:0009311~oligosaccharide metabolic process	4		
+ENSG00000237763/ENSG00000174876/ENSG00000187733 ~ AMY1A/B/C		-	
+ENSG00000127415 ~ IDUA		+	+
+GO:0010677~negative regulation of cellular carbohydrate metabolic process	3		
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000173531 ~ MST1		+	+
+GO:0045912~negative regulation of carbohydrate metabolic process	3		
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000173531 ~ MST1		+	+
+GO:0009756~carbohydrate mediated signaling	2		
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+GO:0005996~monosaccharide metabolic process	4		
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000173531 ~ MST1		+	+
+ENSG00000135226 ~ UGT2B28		-	
+GO:0044262~cellular carbohydrate metabolic process	4		
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000127415 ~ IDUA		+	+
+ENSG00000173531 ~ MST1		+	+
+GO:0010182~sugar mediated signaling pathway	2		
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+GO:0010255~glucose mediated signaling pathway	2		
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+GO:0009757~hexose mediated signaling	2		
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+Lipids			
+GO:0006629~lipid metabolic process	10		
+ENSG00000087008 ~ ACOX3		+	+
+ENSG00000198670 ~ LPA		+	
+ENSG00000180089 ~ TMEM86B		-	-
+ENSG00000137392 ~ CLPS		+	+
+ENSG00000204140 ~ CLPSL1		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+ENSG00000184227 ~ ACOT1		-	
+ENSG00000135226 ~ UGT2B28		-	
+GO:0016803~ether hydrolase activity	1		
+ENSG00000180089 ~ TMEM86B		-	-
+GO:0008202~steroid metabolic process	1		
+ENSG00000135226 ~ UGT2B28		-	
+GO:0006631~fatty acid metabolic process	1		
+ENSG00000184227 ~ ACOT1		-	
+GO:0044255~cellular lipid metabolic process	1		
+ENSG00000180089 ~ TMEM86B		-	-
+GO:0008202~steroid metabolic process	1		
+ENSG00000135226 ~ UGT2B28		-	
+Proteins - Liver			
+GO:0016491~oxidoreductase activity	1		
+ENSG00000169021 ~ UQCRFS1		+	+
+GO:0016627~oxidoreductase activity, acting on the CH-CH group of donors	1		
+ENSG00000087008 ~ ACOX3		+	+
+GO:1990204~oxidoreductase complex	1		
+ENSG00000139515 ~ PDX1		+	+
+GO:0004252~serine-type endopeptidase activity	2		
+ENSG00000109758~HGFAC		+	+
+ENSG00000172236 ~ TPSAB1/B2		-	-
+PC00220~transferase (transaminase activity)	1		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+Small Molecules			
+GO:0055086~nucleobase-containing small molecule metabolic process	6		
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000169021 ~ UQCRFS1		+	+
+ENSG00000169020 ~ ATP5ME		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0009150~purine ribonucleotide metabolic process	6		
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000169021 ~ UQCRFS1		+	+
+ENSG00000169020 ~ ATP5ME		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0045934~negative regulation of nucleobase-containing compound metabolic process	10		
+ENSG00000196705 ~ ZNF431		+	+
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000113196 ~ HAND1			+
+ENSG00000132207/ENSG00000181625 ~ SLX1A/B		-	
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000187837 ~ H1-2			+
+GO:0009259~ribonucleotide metabolic process	6		
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000169021 ~ UQCRFS1		+	+
+ENSG00000169020 ~ ATP5ME		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0034035~purine ribonucleoside bisphosphate metabolic process	2		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0006082~organic acid metabolic process	8		
+ENSG00000087008 ~ ACOX3		+	+
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000127415 ~ IDUA		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+ENSG00000184227 ~ ACOT1		-	
+ENSG00000135226 ~ UGT2B28		-	
+GO:0045721~negative regulation of gluconeogenesis	2		
+ENSG00000173531 ~ MST1		+	+
+GO:0044281~small molecule metabolic process	15		
+ENSG00000180089 ~ TMEM86B		-	-
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000169021 ~ UQCRFS1		+	+
+ENSG00000169020 ~ ATP5ME		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+ENSG00000173531 ~ MST1		+	+
+ENSG00000135226 ~ UGT2B28		-	
+ENSG00000087008 ~ ACOX3		+	+
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000127415 ~ IDUA		+	+
+ENSG00000184227 ~ ACOT1		-	
+GO:0044282~small molecule catabolic process	5		
+ENSG00000087008 ~ ACOX3		+	+
+ENSG00000127415 ~ IDUA		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0060359~response to ammonium ion	3		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0042445~hormone metabolic process	1		
+ENSG00000135226 ~ UGT2B28		-	
+Molecules & Ion Transport			
+GO:0098657~import into cell	1		
+ENSG00000066230 ~ SLC9A3		+	+
+GO:1990573~potassium ion import across plasma membrane	1		
+ENSG00000186009 ~ ATP4B		+	+
+GO:0071805~potassium ion transmembrane transport	1		
+ENSG00000066230 ~ SLC9A3		+	+
+GO:0015079~potassium ion transmembrane transporter activity	1		
+ENSG00000066230 ~ SLC9A3		+	+
+GO:0051139~metal cation:proton antiporter activity	1		
+ENSG00000066230 ~ SLC9A3		+	+
+GO:0043271~negative regulation of monoatomic ion transport	2		
+ENSG00000170379 ~ TACF2		-	
+ENSG00000283528 ~ TACF2C		-	
+GO:0051222~positive regulation of protein transport	2		
+ENSG00000170379 ~ TACF2		-	
+ENSG00000283528 ~ TACF2C		-	
+GO:0033157~regulation of intracellular protein transport	2		
+ENSG00000170379 ~ TACF2		-	
+ENSG00000283528 ~ TACF2C		-	
+GO:0034765~regulation of monoatomic ion transmembrane transport	2		
+ENSG00000170379 ~ TACF2		-	
+ENSG00000283528 ~ TACF2C		-	
+GO:0032412~regulation of monoatomic ion transmembrane transporter activity	2		
+ENSG00000170379 ~ TACF2		-	
+ENSG00000283528 ~ TACF2C		-	
+GO:0035725~sodium ion transmembrane transport	2		
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000066230 ~ SLC9A3		+	+
+GO:0015081~sodium ion transmembrane transporter activity	1		
+ENSG00000066230 ~ SLC9A3		+	+
+GO:1902495~transmembrane transporter complex	1		
+ENSG00000186009 ~ ATP4B		+	+
+Nitrogen			
+GO:0043279~response to alkaloid	3		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000163623 ~ NKX6−1		+	+
+GO:0010243~response to organonitrogen compound	7		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000057593 ~ F7		+	+
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+ENSG00000186009 ~ ATP4B		+	+
+GO:0071870~cellular response to catecholamine stimulus	3		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0071868~cellular response to monoamine stimulus	3		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0071869~response to catecholamine	3		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0071867~response to monoamine	3		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0006584~catecholamine metabolic process	3		
+ENSG00000164107 ~ HAND2			+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0009712~catechol-containing compound metabolic process	3		
+ENSG00000164107 ~ HAND2			+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0006637~acyl-CoA metabolic process	1		
+ENSG00000184227 ~ ACOT1		-	
+GO:1904431~positive regulation of t-circle formation	2		
+ENSG00000132207/ENSG00000181625 ~ SLX1A/B		-	
+Glucoronidation			
+GO:0009812~flavonoid metabolic process	2		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0009410~response to xenobiotic stimulus	5		
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+ENSG00000135226 ~ UGT2B28		-	
+GO:0006805~xenobiotic metabolic process	3		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+ENSG00000135226 ~ UGT2B28		-	
+Sulfur			
+GO:0097428~protein maturation by iron-sulfur cluster transfer	2		
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+GO:0006790~sulfur compound metabolic process	6		
+ENSG00000127415 ~ IDUA		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+ENSG00000184227 ~ ACOT1		-	
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+GO:0051923~sulfation	2		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+Homeostasis			
+GO:0006873~cellular ion homeostasis	7		
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0055082~cellular chemical homeostasis	9		
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0019725~cellular homeostasis	9		
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0048878~chemical homeostasis	10		
+ENSG00000087008 ~ ACOX3		+	+
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000163623 ~ NKX6−1		+	+
+ENSG00000139515 ~ PDX1		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0030003~cellular cation homeostasis	7		
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0006873~cellular ion homeostasis	7		
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0055080~cation homeostasis	7		
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0098771~inorganic ion homeostasis	7		
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0006875~cellular metal ion homeostasis	6		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B			
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0050801~ion homeostasis	7		
+ENSG00000066230 ~ SLC9A3		+	+
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0055065~metal ion homeostasis	6		
+ENSG00000169676 ~ DRD5		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000183336/ENSG00000169627 ~ BOLA2/B		-	
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000272398 ~ CD24			-
+GO:0055074~calcium ion homeostasis	1		
+ENSG00000109501 ~ WFS1		+	+
+Catabolism			
+GO:0019336~phenol-containing compound catabolic process	2		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0018958~phenol-containing compound metabolic process	3		
+ENSG00000164107 ~ HAND2			+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0044712~single-organism catabolic process	9		
+ENSG00000087008 ~ ACOX3		+	+
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000137392 ~ CLPS		+	+
+ENSG00000204140 ~ CLPSL1		+	+
+ENSG00000127415 ~ IDUA		+	+
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+ENSG00000109501 ~ WFS1		+	+
+GO:0034310~primary alcohol catabolic process	2		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0006068~ethanol catabolic process	2		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+GO:0006067~ethanol metabolic process	2		
+ENSG00000261052/ENSG00000213648 ~ SULT1A3/4		-	
+Immunity - Antiobiotic			
+GO:0006955~immune response	13		
+ENSG00000183709/ENSG00000197110 ~ IFNL2/3		-	-
+ENSG00000223638 /ENSG00000229292 ~ RFPL4A/L1		+	+
+ENSG00000173531 ~ MST1		+	+
+ENSG00000244731/ENSG00000224389 ~ C4A/B		+	+
+ENSG00000261371 ~ PECAM1			-
+ENSG00000145911 ~ N4BP3		+	+
+ENSG00000272398 ~ CD24			-
+GO:0006952~defense response	16		
+ENSG00000183709/ENSG00000197110 ~ IFNL2/3		-	-
+ENSG00000223638 /ENSG00000229292 ~ RFPL4A/L1		+	+
+ENSG00000173531 ~ MST1		+	+
+ENSG00000244731/ENSG00000224389 ~ C4A/B		+	+
+ENSG00000228278 ~ ORM2		+	
+ENSG00000229314 ~ ORM1		+	
+ENSG00000172236 ~ TPSAB1/B2		-	-
+ENSG00000145911 ~ N4BP3		+	+
+ENSG00000137331 ~ IER3 (IEX-1)			+
+ENSG00000259823 ~ LYPD8			-
+ENSG00000010327 ~ STAB1		+	+
+GO:0002376~immune system process	17		
+ENSG00000183709/ENSG00000197110 ~ IFNL2/3		-	-
+ENSG00000223638 /ENSG00000229292 ~ RFPL4A/L1		+	+
+ENSG00000173531 ~ MST1		+	+
+ENSG00000244731/ENSG00000224389 ~ C4A/B		+	+
+ENSG00000261371 ~ PECAM1			-
+ENSG00000276966/ENSG00000197837 ~ H4C16/5			+
+ENSG00000145911 ~ N4BP3		+	+
+ENSG00000057593 ~ F7		+	+
+ENSG00000164107 ~ HAND2			+
+ENSG00000272398 ~ CD24			-
+GO:0045087~innate immune response	10		
+ENSG00000244731/ENSG00000224389 ~ C4A/B		+	+
+ENSG00000145911 ~ N4BP3		+	+
+ENSG00000183709/ENSG00000197110 ~ IFNL2/3		-	-
+ENSG00000223638 /ENSG00000229292 ~ RFPL4A/L1		+	+
+ENSG00000173531 ~ MST1		+	+
+GO:0006959~humoral immune response	4		
+ENSG00000244731/ENSG00000224389 ~ C4A/B		+	+
+GO:0098542~defense response to other organism	6		
+ENSG00000183709/ENSG00000197110 ~ IFNL2/3		-	-
+ENSG00000259823 ~ LYPD8			-
+ENSG00000010327 ~ STAB1		+	+
+GO:0009617~response to bacterium	8		
+ENSG00000244731/ENSG00000224389 ~ C4A/B		+	+
+ENSG00000137392 ~ CLPS		+	+
+ENSG00000259823 ~ LYPD8			-
+ENSG00000010327 ~ STAB1		+	+
+ENSG00000186009 ~ ATP4B		+	+
+ENSG00000272398 ~ CD24			-
+GO:2000675~negative regulation of type B pancreatic cell apoptotic process	2		
+ENSG00000109501 ~ WFS1		+	+
+ENSG00000139515 ~ PDX1		+	+
+GO:0002682~regulation of immune system process	12		
+ENSG00000276966/ENSG00000197837 ~ H4C16/5			+
+ENSG00000244731/ENSG00000224389 ~ C4A/B		+	+
+ENSG00000057593 ~ F7		+	+
+ENSG00000228278 ~ ORM2		+	
+ENSG00000229314 ~ ORM1		+	
+ENSG00000183709/ENSG00000197110 ~ IFNL2/3		-	-
+ENSG00000173531 ~ MST1		+	+
+ENSG00000272398 ~ CD24			-